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CARDIOPULMONARY SUPPORT AND PHYSIOLOGY - Tranexamic acid compared with high-dose aprotinin in primary elective heart operations: Effects on perioperative bleeding and allogeneic transfusions - We evaluated the effects of aprotinin and tranexamic acid on postoperative bleeding and the need for allogeneic transfusions in 1040 patients undergoing primary elective heart surgery. No clinical differences were found between the 2 drugs. Because tranexamic acid is 100 times cheaper than aprotinin, its use is preferable in this setting/ / Casati, Valter / C.V. Mosby / Journal of thoracic and cardiovascular s / 520-527p. / 2000

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