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Effect of Single-Dose Prophylactic Ampicillin and Sulbactam on Wound Infection Following Tension-Free lnguinal Hernia Repair With Polypropylene Mesh: The Randomized, Double Blind, Prospective Trial - This study documented a significant (10-fold) decrease in overall wound infections when single-dose, intravenous AS was used during Lichtenstein hernia repair. Deep infections and wound infection-related readmissions were also reduced by the use of AS. Proponents of mesh repairs may therefore be advised to use prophylactic single-dose intravenous antibiotic coverage in the light of the results of this trial. AS proved to be an effective antimicrobial agent./ / Yerdel, Mehmet A / J. B. Lippincott [etc.] / Annals of surgery / 26-33p. / 2001

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