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LABORATORY INVESTIGATIONS - Inhibitory Effects of Barbiturates on Nicotinic Acetylcholine Receptors in Rat Central Nervous System Neurons - The authors found that thiopental and convulsant and depressant isomers of a barbiturate all inhibit native nAchRs in rat medial habenula neurons. The results suggest that inhibition of nicotinic acetylcholine receptors in these neurons is not directly relevant to the hypnotic or anticonvulsive actions of barbiturates./
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