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CLINICAL INVESTIGATIONS - Core Cooling by Central Venous Infusion of Ice-cold (4(degree)C and 20(degree)C) Fluid: Isolation of Core and Peripheral Thermal Compartments - Central venous infusion of 40 ml/kg fluid at 4(degree)C decreased core temperature 2.5(degree)C, which was 0.8(degree)C more than would be expected if the change in body heat content were distributed in proportion to body mass. Administration of cold fluid thus cools the core more than might be expected and may be useful for induction of therapeutic hypothermia/
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