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CARDIOVASCULAR ANESTHESIA - Society of Cardiovascular Anesthesiologists - Optison (FS069) Disrupts the Blood-Brain Barrier in Rats - IMPLICATIONS: Optison appears to disrupt the blood-brain barrier when introduced directly into the cerebral arterial circulation. This may be related to the octafluoropropane gas used in Optison as a contrast medium. Optison should be used with caution when the possibility of a right-to-left shunt exists/
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