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REGIONAL ANESTHESIA AND PAIN MEDICINE - A Comparative Study with Oral Nifedipine, Intravenous Nimodipine, and Magnesium Sulfate in Postoperative Analgesia - IMPLICATIONS: The increase of intracellular calcium plays a key role in spinal transmission of pain and in the establishment of central sensitization. We examined the effects of nifedipine, nimodipine, and magnesium sulfate in postoperative analgesia after colorectal surgery. We found no differences in morphine consumption with the administration of each drug alone/
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