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REGIONAL ANESTHESIA AND PAIN MEDICINE - GENERAL ARTICLES - The Nonimmobilizer 1,2-Dichlorohexafluorocyclobutane Does Not Affect Thermoregulation in the Rat - IMPLICATIONS: Unlike inhaled anesthetics, the nonimmobilizer 2N (1,2-dichlorohexafluorocyclobutane) minimally affects temperature regulation in rats. Thus, 2N may be useful in mechanistic studies of temperature regulation. Cellular and molecular sites that mediate the capacity of inhaled anesthetics to depress thermoregulation should be influenced by anesthetics but not by 2N/
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