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SCIENTIFIC PAPERS - Long-Term Survival After Liver Transplantation in 4,000 Consecutive Patients at a Single Center - Little is known about causes of late graft failure and death in liver transplant patients. The authors compared the impact of factors such as diagnosis, age, sex, and time period of transplantation to the causes of death and graft loss in 4,000 liver transplant recipients over a 20-year period at a single center. Long-term survival was significantly better in the pediatric age group, in female recipients, and in patients transplanted after 1990. Rates of retransplantation for acute or chronic rejection were significantly lower under tacrolimus-based immunosuppression./
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