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CLINICAL INVESTIGATIONS - Tourniquet-induced Changes of Energy Metabolism in Human Skeletal Muscle Monitored by Microdialysis - Microdialysis was used to monitor interstitial levels of metabolites in human skeletal muscle during orthopedic surgery. Tourniquet-induced ischemia caused reductions of glucose and increases of lactate, hypoxanthine, and choline levels. The metabolic changes were more prominent after exsanguination than after circulatory occlusion./
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