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LABORATORY INVESTIGATIONS - Impairment of Cardiac b-Adrenoceptor Cellular Signaling by Decreased Expression of Gsa in Septic Rabbits - The primary defect in the impaired inotropic responsiveness to b-adrenoceptor stimulation in myocardium from rabbits 3-6 h after injection of 100 mg/kg Escherichia coli lipopolysaccharide resides at the levels of Gsa protein and messenger RNA./
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