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CLINICAL INVESTIGATIONS - Tranexamic Acid Administration after Cardiac Surgery: A Prospective, Randomized, Double-blind, Placebo-controlled Study - In cardiac surgical patients who were administered tranexamic acid during surgery, the continued administration of tranexamic acid for 12 h postoperatively did not reduce blood loss compared with patients administered postoperative placebo (saline). Prolonged postoperative treatment with tranexamic acid offers no advantages of treatment limited to the intraoperative period./
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