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LABORATORY INVESTIGATIONS - Effect of Drugs Used for Neuropathic Pain Management on Tetrodotoxin-resistant Na+ Currents in Rat Sensory Neurons - Depolarized resting membrane potential and repetitive stimulation has little effect on current amplitude of tetrodotoxin-resistant Na+ channels but renders the channels highly sensitive to the use-dependent blockers lidocaine, mexiletine, and amitriptyline./
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