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CARDIOVASCULAR ANESTHESIA - (Society of Cardiovascular Anesthesiologists) - CASE REPORT - Plasma Tranexamic Acid Concentrations During Cardiopulmonary Bypass - IMPLICATIONS: A 10 mg/kg initial dose of tranexamic acid followed by an infusion of 1 mg.kg-1.h-1 produced plasma concentrations throughout the cardiopulmonary bypass period sufficient to inhibit fibrinolysis in vitro. The dosing of tranexamic acid may require adjustment for renal insufficiency./
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