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LABORATORY INVESTIGATIONS - Effects of Halothane on Sarcoplasmic Reticulum Calcium Release Channels in Porcine Airway Smooth Muscle Cells - Airway smooth muscle relaxation by volatile anesthetics is found to be mediated by depletion of Ca2+ in the sarcoplasmic reticulum via increased leak through inositol trisphosphate and ryanodine receptor channels./
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