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CARDIOPULMONARY SUPPORT AND PHYSIOLOGY - P-selectin participates in cardiopulmonary bypass-induced inflammatory response in association with nitric oxide and peroxynitrite production - The anti-inflammatory effect of P-selectin monoclonal antibody on cardiopulmonary bypass (CPB)-induced inflammatory response was demonstrated in a rat CPB model by measuring P-selectin, inflammatory cytokines, nitrate/nitrite, nitrotyrosine, and respiratory index. P-selectin may help to augment CPB-induced inflammatory response in association with nitric oxide and peroxynitrite/
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