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EVIDENCE-BASED REVIEW - Bisphosphonates in the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis The detrimental effects of chronic glucocorticoid use on bone mineral density are well recognized, but there is scant evidence for the effectiveness of strategies to prevent osteoporosis in these patients. The authors of this review describe the evidence for the use of oral bisphosphonates in the prevention and treatment of glucocorticoid-induced osteoporosis in adults./
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