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Basic Science - Immunophenotypic Analysis of the Inflammatory Infiltrates in Herniated Intervertebral Discs - Patterns of progression of spinal deformity in 12 patients with Duchenne muscular dystrophy (DMD) were examined in a retrospective, longitudinal study. Multiple discriminant analysis was conducted to discriminate patients with severe progression of spinal deformity from those with lesser progression using four predictors: 1) vital capacity at the age of 10 years, 2) the age at which ambulation ceased, 3) curve pattern of spinal scoliosis, and 4) Cobb angles of spinal scoliosis at the age of 10 years. Discriminant analysis correctly predicted the severity of the clinical course of 91.7% of the DMD patients. Vital capacity at age 10 was found to be the strongest predictor among the variables./
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