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The Progression of Fenfluramine-Associated Valvular Heart Disease Assessed by Echocardiography In 50 patients who had developed at least mild mitral regurgitation or aortic regurgitation after exposure to fenfluramines, serial echocardiography showed that valvular regurgitation improved or remained stable in most patients after therapy was discontinued. Worsening of valvular regurgitation was uncommon./
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