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Basic Science - Prevention of Compartment Syndrome in Dorsal Root Ganglia Caused by Exposure to Nucleus Pulposus - Endoneurial fluid pressure in the dorsal root ganglia after application of nucleus pulposus with pentoxifylline or physiologic saline solution (control) were measured using the servo-null micropipette system. Pentoxifylline, an antitumor necrosis factor-a drug, prevented the dorsal root ganglion compartment syndrome caused by topical application of nucleus pulposus. Anti-inflammatory cytokine therapy may become an effective treatment of sciatica because of disc herniation./
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