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Biomechanics - Effect of Endplate Conditions and Bone Mineral Density on the Compressive Strength of the Graft-Endplate Interface in Anterior Cervical Spine Fusion - Destructive compression tests and finite element analyses were conducted to investigate the effect of endplate thickness, end-plate holes, and bone mineral density of the vertebral body on the biomechanical strength of the endplate-graft interface in an anterior cervical spine fusion. Results of this study suggest that it is important to preserve the endplate as much as possible to prevent graft subsidence into the vertebral body, particularly in patients with poor bone quality. It is preferable to make one central bole rather than multiple smaller holes in the endplate for vascularity of the bone graft because it reduces the surface area exposed to fracture stresses./
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