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Intestinal Metaplasia in Patients With Columnar Line Esophagus is Associated With High Levels of Duodenogastroesophageal Reflux - Why some patients with columnar lined esophagus develope intestinal metaplasia and others do not it is still unknown. The authors studied the acid and duodenal reflux to the esophagus in 15 healthy volunteers and 65 patients with gastro-esophageal reflux disease (10 gastro-esophageal reflux without esophagitis, 20 with esophagitis, and 35 with columnar lined esophagus). Duodenogastroesophageal reflux was greater in the columnar lined esophagus patients presenting with intestinal metaplasia./
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