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ORIGINAL ARTICLES - Expression of Adrenocorticotropin Receptor Gene in Adrenocortical Adenomas From Patients With Cushing Syndrome: Possible Contribution for the Autonomous Production of Cortisol - Endogenous ACTH secretion is suppressed in patients with Cushing's syndrome due to adrenocortical adenoma. Likewise, expression of ACTH-R mRNA was suppressed in the normal gland attached to the adenoma, but not in the adenoma itself. This result indicates a possible role of ACTH-R in the autonomous production of cortisol from the adenoma./
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