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SCIENTIFIC PAPERS - Dermal Injection of Radioactive Colloid Is Superior to Peritumoral Injection for Breast Cancer Sentinel Lymph Node Biopsy: Results of a Multiinstitutional Study - The optimal injection technique for breast cancer SLN biopsy remains to be defined. Although dermal injection of radioactive colloid has been proposed, no published data are available to establish the false negative rate associated with this technique. In this large multi-center study, we compared dermal, subdermal, and peritumoral injection of radioactive colloid. Dermal injection of radioactive colloid significantly improves the SLN identification rate and minimizes the false negative rate. Dermal injection also is associated with SLN that are five- to seven-fold more radioactive than with peritumoral injection, which simplifies SLN localization and may shorten the learning curve./ / McMasters, Kelly M / J. B. Lippincott [etc.] / Annals of surgery / 676-687p. / 2001

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