충남대학교 외국학술지지원센터

주메뉴 바로가기
본문 바로가기(skip to content)
퀵메뉴 바로가기
마이메뉴 바로가기
도서관정보 바로가기

글로벌메뉴

주메뉴

이용안내
원문검색
센터소개
- 소개
- 연혁
- 운영시간
- 조직
게시판
- 이용안내
- 원문검색
- 센터소개
  - 소개
  - 연혁
  - 운영시간
  - 조직
- 게시판

저장/메일/인쇄

|Home >
저장/메일/인쇄

검색간략리스트

SCIENTIFIC PAPERS - High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells - DPC4 (deleted in pancreatic carcinoma, locus 4 or MADH4/SMAD4) is a tumor-suppressor gene mutated in approximately half of human pancreatic adenocarcinomas. The current study reports the use of a stably integrated DPC4-reporter system in human pancreatic cells to screen a library of 16,320 random compounds, searching for chemicals that interact with the DPC4 tumor-suppressive pathway. The screening identified several compounds capable of augmenting and inhibiting DPC4-specific luciferase reporter activity. The identification of such compounds will enable us to further understand this critical signal transduction pathway and may identify potential candidates for rational therapeutic intervention./ / Sohn, Taylor A / J. B. Lippincott [etc.] / Annals of surgery / 696-703p. / 2001

항목 : 간략정보 상세정보 도서정보 초록 목차

이메일 : 제목 :

하단메뉴