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TECHNOLOGY, COMPUTING, AND SIMULATION - (Society for Technology in Anesthesia) - CRITICAL CARE AND TRAUMA - Ventilator-Induced Lung Injury Is Associated with Neutrophil Infiltration, Macrophage Activation, and TGF-b1 mRNA Upregulation in Rat Lungs - IMPLICATIONS: High-pressure ventilation demonstrated, in the early phase, not only proinflammatory processes, including neutrophil infiltration and adhesion molecules upregulation on macrophages, but profibriogenetic processes, including transforming growth factor-bl mRNA expression in the lung tissue. These immunological alterations may be involved in the progress of ventilator-induced lung injury./ / Imanaka, Hideaki / International Anesthesia Research Society] / Anesthesia and analgesia / 428-436p. / 2001

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