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Substrate-induced Conformational Changes in the Transmembrane Segments of Human P-glycoprotein. DIRECT EVIDENCE FOR THE SUBSTRATE-INDUCED FIT MECHANISM FOR DRUG BINDING
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Loo, T. W.; Bartlett, M. C.; Clarke, D. M.
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WAVERLY PRESS INC
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2003
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2 |
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Drug Binding in Human P-glycoprotein Causes Conformational Changes in Both Nucleotide-binding Domains
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Loo, T. W.; Bartlett, M. C.; Clarke, D. M.
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WAVERLY PRESS INC
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2003
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3 |
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Permanent Activation of the Human P-glycoprotein by Covalent Modification of a Residue in the Drug-binding Site
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Loo, T. W.; Bartlett, M. C.; Clarke, D. M.
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WAVERLY PRESS INC
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2003
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4 |
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Introduction of the most common cystic fibrosis mutation (DeltaF508) into human P-glycoprotein disrupts packing of the transmembrane segments
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Loo, T. W.; Bartlett, M. C.; Clarke, D. M.
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WAVERLY PRESS INC
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2002
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5 |
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The "LSGGQ" Motif in Each Nucleotide-binding Domain of Human P-glycoprotein Is Adjacent to the Opposing Walker A Sequence
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Loo, T. W.; Bartlett, M. C.; Clarke, D. M.
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WAVERLY PRESS INC
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2002
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