131 |
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Communications - Synthesis of a Substance P Antagonist with a Somatostatin Scaffold: Factors Affecting Agonism/Antagonism at GPCRs and the Role of Pseudosymmetry/
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Liu, Josephine
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American Chemical Society
|
2000
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|
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132 |
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Expedited Articles - Discovery of a Potent, Orally Bioavailable b3 Adrenergic Receptor Agonist, (R)-N-(4-(2-((2-Hydroxy-2-(3-pyridinyl)ethyl)amino)ethyl)- phenyl)-4-(4-(4-(trifluoromethyl)phenyl)-thiazol- 2-yl)benzenesulfonamide/
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Mathvink, Robert J
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American Chemical Society
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2000
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|
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133 |
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The Novel Silatecan 7-tert-Butyldimethylsilyl-10-hydroxycamptothecin Displays High Lipophilicity, Improved Human Blood Stability, and Potent Anticancer Activity/
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Bom, David
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American Chemical Society
|
2000
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134 |
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Synthesis, Biological Evaluation, and Conformational Analysis of A-Ring Diastereomers of 2-Methyl-1,25-dihydroxy-vitamin D3 and Their 20-Epimers: Unique Activity Profiles Depending on the Stereochemistry of the A-Ring and at C-20/
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Konno, Katsuhiro
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American Chemical Society
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2000
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135 |
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Expedited Articles - (-)Spiro(1-azabicyclo(2.2.2)octane-3,5'-oxazolidin-2'-one), a Conformationally Restricted Analogue of Acetylcholine, Is a Highly Selective Full Agonist at the a7 Nicotinic Acetylcholine Receptor/
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Mullen, George
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American Chemical Society
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2000
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136 |
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Resistance-Modifying Agents. 9. Synthesis and Biological Properties of Benzimidazole Inhibitors of the DNA Repair Enzyme Poly(ADP-ribose) Polymerase/
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White, Alex W
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American Chemical Society
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2000
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137 |
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2D QSAR Modeling and Preliminary Database Searching for Dopamine Transporter Inhibitors Using Genetic Algorithm Variable Selection of Molconn Z Descriptors/
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Hoffman, Brian T
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American Chemical Society
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2000
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|
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138 |
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Novel Bronchodilators: Synthesis, Transamination Reactions, and Pharmacology of a Series of Pyrazino(2,3-c)(1,2,6)thiadiazine 2,2-Dioxides/
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Campillo, Nuria
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American Chemical Society
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2000
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139 |
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Brief Articles - Hydrolytic Stability versus Ring Size in Lactams: Implications for the Development of Lactam Antibiotics and Other Serine Protease Inhibitors/
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Imming, Peter
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American Chemical Society
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2000
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140 |
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Structure-Activity Relationships of a Series of Pyrrolo(3,2-d)pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists/
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Norman, Mark H
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American Chemical Society
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2000
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