충남대학교 외국학술지지원센터

글로벌메뉴

전체 ㅣ A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ㅣ 가 나 다 라 마 바 사 아 자 차 카 타 파 하 기타

검색어[가나다ABC : 전체]

총 2건 중 2건 출력

1/1 페이지

서명: Intraductal Papillary Mucinous Neoplasms of the Pancreas: An Increasingly Recognized Clinicopathologic Entity/
저자: Sohn, Taylor A
발행처: J. B. Lippincott [etc.]
원문제공시작년: 2001
자료유형: 저널기사 원문복사 신청
원문제공마감년

서명: SCIENTIFIC PAPERS - High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells - DPC4 (deleted in pancreatic carcinoma, locus 4 or MADH4/SMAD4) is a tumor-suppressor gene mutated in approximately half of human pancreatic adenocarcinomas. The current study reports the use of a stably integrated DPC4-reporter system in human pancreatic cells to screen a library of 16,320 random compounds, searching for chemicals that interact with the DPC4 tumor-suppressive pathway. The screening identified several compounds capable of augmenting and inhibiting DPC4-specific luciferase reporter activity. The identification of such compounds will enable us to further understand this critical signal transduction pathway and may identify potential candidates for rational therapeutic intervention./
저자: Sohn, Taylor A
발행처: J. B. Lippincott [etc.]
원문제공시작년: 2001
자료유형: 저널기사 원문복사 신청
원문제공마감년

임시보관함보기